Molecular Neurogenetics Unit, IRCCS Foundation, C. Besta Neurological Institute, Via L. Temolo n. 4, 20126, Milan, Italy. Department of Medicine and Surgery, PhD Programme in Molecular and Translational Medicine, Milan Bicocca University, Via Cadore 48, 20900, Monza, Italy. IRCCS Fondazione Stella Maris, Calambrone, Pisa, Italy. Department of Experimental Medicine, University of Pisa, Pisa, Italy. Medical Genetics Unit, San'Orsola-Malpighi University Hospital, Via Giuseppe Massarenti 9, 40138, Bologna, Italy. Neuroradiology, Foundation IRCCS, Neurological Institute "C. Besta", Milan, Italy. Medical Genetics Unit, Sant'Orsola-Malpighi University Hospital, Department of Medical and Surgical Sciences, University of Bologna, Via Giuseppe Massarenti 9, 40138, Bologna, Italy. Child Neurology Unit, Foundation IRCCS, Neurological Institute C. Besta, Milan, Italy. Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. Molecular Neurogenetics Unit, IRCCS Foundation, C. Besta Neurological Institute, Via L. Temolo n. 4, 20126, Milan, Italy. valeria.tiranti@istituto-besta.it.